Low ventilation leads to increased level of moisture and pollutants in a home. It is not a practical idea to constantly inspect the indoor air for dangerous level of pollutants. The best protection is having background ventilation to constantly remove indoor air and replace it with fresher outdoor air. And this job is done by the HVAC and its ventilation duct.
In all houses heating and cooling unit eats up the largest chunk in the energy-use pie chart. Therefore it is more than important to make the insulation in the house foolproof to prevent wastage of costly energy. The HVAC system with its duct work and other paraphernalia should be designed so that it will not allow seepage of air to the surrounding and at the same time allow external air to make its way inside the house in order to replace the stale air. Proper ventilation keeps issues such as mold, wood decay, rusting, at bay. Poor ventilation can lead to ill-health of the occupants who can contract allergies, pneumonia, fatigue, nausea, dry eyes, headaches and nasal congestion. It can cause frosting and bad odor in the house. It will make your machine work harder to keep up the cooling level which will cause rapid wear and tear.